Biomechanics of the Gravid Human Uterus by Roustem N. Miftahof download in pdf, ePub, iPad
The main functional link in the cascade of processes is intracellular free calcium. Reprinted with permission from Ref. Two types of constitutive relationships were considered, i. Most of the uterus is made up of the myometrium.
There is no compelling experimental evidence to support their existence in the human myometrium. Actin filaments are single helical coils of actin associated with tropomyosin and caldesmon. Net myometrial contractile activity is determined by the balance of receptors present. The former sustains the spread of the wave of depolarization in the organ, the latter its contractility.
An agreement between theoretical results and in vivo clinical measurements was achieved through multiple numerical experiments and adjustments of input parametric data. Its cavity is larger than in the pre-pregnant state, vessels are tortuous, and muscular layers are more prominent.
The level depends on their gestational status, i. Deformations were small, but displacements were finite. The fundus is the upper part of the uterus. The following synthetic phase is remarkable for myometrial cell hypertrophy associated with increased synthesis and deposition of interstitial matrix. Their overall effect is the maintenance of the resting membrane potential at a constant level and inhibition of phasic uterine contractions.
Another part of the uterus is the body. The axial load was defined a priori as a function of time. It was assumed that the uterus underwent axisymmetric deformations throughout. It also has fluid and the placenta inside.
The cervix constituted a viscoelastic two-compartment continuum. These changes were associated with the transformation of the uterus from a pearlike to more spherical shape. The big arteries are the internal iliac arteries. Its actual configuration, though, before labor greatly depends on the position of the fetus and the amount of amniotic fluid.
It provides stability for the propagation of excitation and the coordination of motility. The smaller arteries give blood to all the layers of the uterus.
It is tilted forward in most women. However, no comparison to real experimental data was made.
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